Invitrogen™ ATXN1L Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA549084

Catalog No. PA549084

Description

Predicted to react with mouse based on sequence homology.

Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression (PubMed:21475249). Can suppress ATXN1 cytotoxicity in spinocerebellar ataxia type 1 (SCA1). In concert with CIC and ATXN1, involved in brain development. [UniProt].

Specifications

• Antigen: ATXN1L
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ATXN1L
• Gene Alias: ankyrin repeat and SOCS box containing 16; ankyrin repeat and SOCS box protein 16; ankyrin repeat and SOCS box-containing 16; ankyrin repeat and SOCS box-containing protein 16; ASB16; ASB-16; ataxin 1 like; ataxin 1-like; ataxin-1-like; ATXN1L; BOAT; BOAT1; Brother of ataxin-1; brother of ATXN1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 342371
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P0C7T5
• Gene Symbols: ATXN1L
• Immunogen: KLH conjugated synthetic peptide between 385-411 amino acids from the Central region of human ATXN1L.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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