Invitrogen™ ATXN1L Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA566532

Catalog No. PIPA566532

Description

Immunogen sequence: HPGIHYPPLHY AQLPSTSLQF IGSPYSLPYA VPPNFLPSPL LSPSANLATS HLPHFVPYAS LLAEGATPP Highest antigen sequence identity to the following orthologs - mouse 96%, rat 93%.

Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression (PubMed:21475249). Can suppress ATXN1 cytotoxicity in spinocerebellar ataxia type 1 (SCA1). In concert with CIC and ATXN1, involved in brain development. [UniProt].

Specifications

• Antigen: ATXN1L
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ATXN1L
• Gene Alias: ankyrin repeat and SOCS box containing 16; ankyrin repeat and SOCS box protein 16; ankyrin repeat and SOCS box-containing 16; ankyrin repeat and SOCS box-containing protein 16; ASB16; ASB-16; ataxin 1 like; ataxin 1-like; ataxin-1-like; ATXN1L; BOAT; BOAT1; Brother of ataxin-1; brother of ATXN1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 342371
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P0C7T5
• Gene Symbols: ATXN1L
• Immunogen: Recombinant Human ATXN1L. Recombinant protein control fragment (Product #RP-107195).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov