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ATXN7L3B Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501989318
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100 μL
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Catalog No. Quantity
50-198-9318 100 μL
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Catalog No. 50-198-9318 Supplier Bioss Supplier No. BS9754R
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Description

Rabbit Polyclonal Antibody

By binding to ENY2, interferes with the nuclear functions of the deubiquitinase (DUB) module of the SAGA complex which consists of ENY2, ATXN7, ATXN7L3 and the histone deubiquitinating component USP22. Affects USP22 DUB activity toward histones indirectly by changing the subcellular distribution of ENY2 and altering ENY2 availability for ATXN7L3 interaction. Regulates H2B monoubiquitination (H2Bub1) levels through cytoplasmic sequestration of ENY2 resulting in loss of nuclear ENY2-ATXN7L3 association which destabilizes ATXN7L3. Affects protein expression levels of ENY2 and ATXN7L3.

Specifications

Antigen ATXN7L3B
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene ATXN7L3B
Gene Accession No. Q96GX2
Gene Alias ataxin 7 like 3B; ataxin 7-like 3B; Ataxin-7-like protein 3B; ATXN7L3B; lnc-SCA7; putative ataxin-7-like protein 3B
Gene Symbols ATXN7L3B
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human ATXN7L3B.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 552889
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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