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  6. Invitrogen™ Aurora A Monoclonal Antibody (1A11)

Invitrogen™ Aurora A Monoclonal Antibody (1A11)
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Catalog No. PIMA547380
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250 μL
500 μL
2.5 mL
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Catalog No. Quantity
PIMA547380 250 μL
PIMA547283 2.5 mL
PIMA547379 500 μL
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Catalog No. PIMA547380 Supplier Invitrogen™ Supplier No. MA547380
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Description

Mouse Monoclonal Antibody

Aurora A Monoclonal Antibody for Western Blot, ICC/IF, IHC

AURKA (Aurora A) is a serine/threonine kinase that regulates mitosis by association in vivo with centrosomes. Overexpression of AURKA is observed in many types of cancer. Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment. Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Aurora A
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 1A11
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation cell culture media with 5mM sodium azide
Gene AURKA
Gene Accession No. O14965, P97477
Gene Alias Aik; Airk; AIRK1; Ark1; ARK-1; AU019385; AURA; AURAK; AURKA; Aurora 2; aurora A; Aurora A Kinase; aurora family kinase 1; Aurora kinase A; aurora/IP; aurora/IPL1-like kinase; aurora/IPL1-related kinase 1; AURORA2; Aurora-A; aurora-related kinase 1; AW539821; Ayk1; Breast tumor-amplified kinase; BTAK; EC 2.7.11.1; hARK1; IAK; IAK1; Ipl1- and aurora-related kinase 1; IPL1-related kinase; MGC34538; OTTHUMP00000031341; OTTHUMP00000166072; PPP1R47; protein phosphatase 1, regulatory subunit 47; ratAurA; RP5-1167H4.6; sereine threonine kinase; serine/threonine kinase 6; serine/threonine protein kinase 15; serine/threonine protein kinase 6; serine/threonine-protein kinase 15; Serine/threonine-protein kinase 6; serine/threonine-protein kinase 6; aurora kinase A; serine/threonine-protein kinase aurora-A; Serine/threonine-protein kinase Ayk1; STK15; STK6; STK7; Unknown (protein for MGC:134472)
Gene Symbols AURKA
Host Species Mouse
Immunogen Full length recombinant human aurora A expressed in and purified from E. coli.
Quantity 250 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20878, 6790
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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