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Aurora A Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A300070AT

Encompass_Preferred

Catalog No. 50-155-6834


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Description

Description

The recommended shelf life for this product is 1 year from date of receipt.

Aurora A is a 46 kDa protein that plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines. Multiple transcript variants encoding the same protein have been found for this gene. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal.
Specifications

Specifications

Aurora A
Polyclonal
Unconjugated
AURKA
AIK, ARK1, AURA, AURORA2, BTAK, MGC34538, STK15, STK6, STK7
Rabbit
Antigen affinity chromatography
RUO
6790
4° C
Liquid
Immunoprecipitation
1 mg/ml
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
O14965
AURKA
Between 50 and 100
10 μL
Primary
Human
Antibody
IgG
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