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AVPR2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501980626
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50-198-0626 100 μL
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Catalog No. 50-198-0626 Supplier Bioss Supplier No. BS10014R
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Description

Rabbit Polyclonal Antibody

Avpr2 is a precursor protein consisting of arginine vasopressin and two associated proteins, neurophysin 2 and a glycopeptide, copeptin. Arginine vasopressin is a posterior pituitary hormone which is synthesized in the supraoptic nucleus and paraventricular nucleus of the hypothalamus. Along with its carrier protein, neurophysin 2, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis where it is either stored or secreted into the bloodstream. The precursor is thought to be activated while it is being transported along the axon to the posterior pituitary. Arginine vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. Avpr2 has a direct antidiuretic action on the kidney, and also causes vasoconstriction of the peripheral vessels. Avpr2 can contract smooth muscle during parturition and lactation. Avpr2 is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. The activity of Avpr2 is mediated by G proteins which activate adenylate cyclase.

Specifications

Antigen AVPR2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene AVPR2
Gene Accession No. P30518
Gene Alias ADHR; Antidiuretic hormone receptor; arginine vasopressin receptor 2; Avp2r; AVPR V2; AVPR2; DI1; DIR; DIR3; MGC126533; MGC138386; ND1; NDI; nephrogenic diabetes insipidus; Renal-type arginine vasopressin receptor; V2r; V2-renal V2R; Vasopressin receptor V2; Vasopressin V2 receptor; VPV2R
Gene Symbols AVPR2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human AVPR2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 554
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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