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Invitrogen™ AXIN1 Monoclonal Antibody (K.53.7)
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Catalog No. PIMA514854
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100 μL
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PIMA514854 100 μL
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Catalog No. PIMA514854 Supplier Invitrogen™ Supplier No. MA514854
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Description

Rabbit Monoclonal Antibody

It is not recommended to aliquot this antibody.

AXIN1 is a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a disheveled and axin (DIX) domain and is thought to function as a negative regulator of the WNT signaling pathway that regulates embryonic axis formation. AXIN1 interacts with adenomatosis polyposis coli (APC), beta-catenin, glycogen synthase kinase 3 beta, forming a tetrameric complex resulting in the regulation of the stabilization of beta-catenin. Mutations in the AXIN1 gene have been associated various carcinomas, indicating that it also functions as a tumor suppressor.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AXIN1
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone K.53.7
Concentration 40 μg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 50% glycerol, 100 μg/mL BSA, 0.15M NaCl and <0.02% sodium azide, pH 7.5
Gene AXIN1
Gene Accession No. O15169, O35625, O70239
Gene Alias AI316800; AXIN; axin 1; Axin1; axin-1; Axis inhibition protein 1; axis inhibitor 1; Fu; fused; fused, mouse, homolog of; GSK-3beta interacting protein rAxin; hAxin; Kb; Ki; kinky; knobbly; LA16c-314G4.3; MGC52315; PPP1R49; Protein Fused; protein phosphatase 1, regulatory subunit 49; rAxin
Gene Symbols AXIN1
Host Species Rabbit
Immunogen Recombinant human Axin1.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12005, 79257, 8312
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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