Axin1 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-4729	100 μL

Catalog No. 50-198-4729 Supplier Bioss Supplier No. BS2439R

Description

Rabbit Polyclonal Antibody

AXIN1 is a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a disheveled and axin (DIX) domain and is thought to function as a negative regulator of the WNT signaling pathway that regulates embryonic axis formation. AXIN1 interacts with adenomatosis polyposis coli (APC), beta-catenin, glycogen synthase kinase 3 beta, forming a tetrameric complex resulting in the regulation of the stabilization of beta-catenin. Mutations in the AXIN1 gene have been associated various carcinomas, indicating that it also functions as a tumor suppressor.

Specifications

• Antigen: Axin1
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: AXIN1
• Gene Accession No.: O15169
• Gene Alias: AI316800; Axin; axin 1; AXIN1; Axin-1; Axis inhibition protein 1; axis inhibitor 1; Fu; fused; fused, mouse, homolog of; GSK-3beta interacting protein rAxin; hAxin; Kb; Ki; kinky; knobbly; LA16c-314G4.3; MGC52315; PPP1R49; Protein Fused; protein phosphatase 1, regulatory subunit 49; rAxin
• Gene Symbols: AXIN1
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human Axin1 .
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 8312
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG