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AXIN1 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501731016 Shop All Proteintech Group Inc Products
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50-173-1016 150 μL
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Catalog No. 50-173-1016 Supplier Proteintech Group Inc Supplier No. 165411AP150UL
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Description

Rabbit Polyclonal Antibody

Proteintech's AXIN1 antibody 16541-1-AP is a rabbit polyclonal antibody raised against the N-terminus of human AXIN1.

AXIN1 is a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a disheveled and axin (DIX) domain and is thought to function as a negative regulator of the WNT signaling pathway that regulates embryonic axis formation. AXIN1 interacts with adenomatosis polyposis coli (APC), beta-catenin, glycogen synthase kinase 3 beta, forming a tetrameric complex resulting in the regulation of the stabilization of beta-catenin. Mutations in the AXIN1 gene have been associated various carcinomas, indicating that it also functions as a tumor suppressor.

Specifications

Antigen AXIN1
Applications Western Blot
Classification Polyclonal
Concentration 0.16 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene AXIN1
Gene Accession No. O15169
Gene Alias AXIN, axin 1, AXIN1, Axis inhibition protein 1, hAxin
Gene Symbols AXIN1
Host Species Rabbit
Immunogen AXIN1 Fusion Protein Ag9858
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8312
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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