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  5. Tocris Bioscience™ AZ 10397767

Tocris Bioscience™ AZ 10397767
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Catalog No. 587210
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58-721-0 10 mg
58-725-0 50 mg
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Catalog No. 58-721-0 Supplier Tocris Bioscience™ Supplier No. 5872/10
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Description

Potent CXCR2 antagonist

AZ 10397767 is a potent CXCR2 antagonist (IC50 = 1 nM); attenuates oxaliplatin -induced NF-κB activation, increases oxaliplatin cytotoxicity, and potentiates oxaliplatin-induced apoptosis in AIPC cells. Reduces the numbers of neutrophils infiltrating into tumors in both in vitro and in vivo models and delayed tumor growth. Orally bioavailable.

Specifications

CAS 333742-63-5
Quantity 10 mg
Target Chemokine Receptor
Molecular Formula C15H14ClFN4O2S2
Formula Weight 400.88g/mol
Product Type Antagonist

For Research Use Only

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