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  5. Tocris Bioscience™ AZ 10606120 dihydrochloride

Tocris Bioscience™ AZ 10606120 dihydrochloride
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Catalog No. 332310
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33-231-0 10 mg
33-235-0 50 mg
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Catalog No. 33-231-0 Supplier Tocris Bioscience™ Supplier No. 3323/10
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Description

Potent P2X7 receptor antagonist

Potent P2X7 receptor antagonist (KD values are 1.4 and 19 nM at human and rat P2X7 receptors respectively). Binds in a positive cooperative manner to sites distinct from, but coupled to, the ATP binding site and acts as a negative allosteric modulator. Inhibits tumor growth and displays antiangiogenic effects in mice.

Chemical Identifiers

CAS 607378-18-7
Molecular Formula C25H36Cl2N4O2

Specifications

Quantity 10 mg
Formula Weight 495.48
Purity >98%
Molecular Weight (g/mol) 495.489
Chemical Name or Material AZ 10606120 dihydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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