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Tocris Bioscience™ AZ 20
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Catalog No. 519850
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10 mg
50 mg
Catalog No. Quantity
51-985-0 50 mg
51-981-0 10 mg
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Catalog No. 51-985-0

Supplier: Tocris Bioscience™ 5198/50

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Potent and selective ATR kinase inhibitor; antitumor

AZ 20 is a potent and selective ATR kinase inhibitor (IC50 = 5 nM). Exhibits 7.6-fold selectivity over mTOR and selectivity over a panel of 442 kinases, including ATM kinase, PI3-K isoforms, and DNA-PK. Inhibits cell growth in cell lines with high baseline levels of replication stress. Displays antitumor effects in vivo.

Specifications

Quantity 50 mg
Product Type AZ 20
Purity >98%
Molecular Weight (g/mol) 412.51
Inhibitors AZ 20

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