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  5. Tocris Bioscience™ AZ 20

Tocris Bioscience™ AZ 20
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Catalog No. 519850
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent and selective ATR kinase inhibitor; antitumor

AZ 20 is a potent and selective ATR kinase inhibitor (IC50 = 5 nM). Exhibits 7.6-fold selectivity over mTOR and selectivity over a panel of 442 kinases, including ATM kinase, PI3-K isoforms, and DNA-PK. Inhibits cell growth in cell lines with high baseline levels of replication stress. Displays antitumor effects in vivo.

Specifications

Quantity 50 mg
Product Type AZ 20
Purity >98%
Molecular Weight (g/mol) 412.51
Inhibitors AZ 20

For Research Use Only

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