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Tocris Bioscience™ AZ 3146

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Quantity:
10 mg
50 mg
Description
Potent and selective monopolar spindle 1 (Mps1) kinase inhibitor (IC50 = 35 nM). Displays selectivity over 46 other kinases including Cdk1 and aurora kinase B. Interferes with chromosome alignment and overrides spindle assembly checkpoint. Inhibits the recruitment of Mad1, Mad2 and centromere protein E (CENP-E) to kinetochores.
Specifications
Specifications
Quantity | 10 mg |
Formula Weight | 452.55 |
Purity | >99% |
Molecular Weight (g/mol) | 452.559 |
Chemical Name or Material | AZ 3146 |
Safety and Handling
Recommended Storage | Store at +4°C |
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