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  5. Tocris Bioscience™ AZ 6102

Tocris Bioscience™ AZ 6102
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Catalog No. 577510
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57-751-0 10 mg
57-755-0 50 mg
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Catalog No. 57-751-0 Supplier Tocris Bioscience™ Supplier No. 5775/10
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Description

Potent TNKS1/2 inhibitor

AZ 6102 is a potent TNKS2 and TNKS1 inhibitor (IC50 values are 1 and 3 nM, respectively). Exhibits >100-fold selectivity for TNKS1/2 over PARP-1, PARP-2 and PARP-6. Inhibits Wnt signaling in DLD-1 cells (IC50 = 5 nM). Exhibits moderate oral bioavailability.

Specifications

Chemical Name or Material rel-2-[4-[6-[(3R,5S)-3,5-Dimethyl-1-piperazinyl]-4-methyl-3-pyridinyl]phenyl]-3,7-dihydro-7-methyl-4H-pyrrolo[2,3-d]pyrimidin-4-one
CAS 1645286-75-4
Quantity 10 mg
Target Tankyrase Inhibitors
Molecular Formula C25H28N6O
Formula Weight 428.53
Purity >98%
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