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Tocris Bioscience™ AZD 3988
Potent and selective DGAT-1 inhibitor
Supplier: Tocris Bioscience™ 4837/10
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Description
AZD 3988 is a potent and selective diacylglycerol acyltransferase (DGAT-1) inhibitor (IC50 = 0.6 nM). Exhibits selectivity for DGAT-1 over DGAT-2, Kv11.1 (hERG) and cytochrome P450 enzymes. Suppresses triacylglyceride (TAG) plasma excursion and adipose tissue TAG synthesis in rats. Reduces body weight of diet-induced obese rats. Cell permeable and orally bioavailable.Specifications
>98% | |
AZD 3988 | |
AZD 3988 |
10 mg | |
456.44 |
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