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Tocris Bioscience™ AZD 3988
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Catalog No. 483710
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Catalog No. Quantity
48-371-0 10 mg
48-375-0 50 mg
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Catalog No. 48-371-0 Supplier Tocris Bioscience™ Supplier No. 4837/10
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Description

Potent and selective DGAT-1 inhibitor

AZD 3988 is a potent and selective diacylglycerol acyltransferase (DGAT-1) inhibitor (IC50 = 0.6 nM). Exhibits selectivity for DGAT-1 over DGAT-2, Kv11.1 (hERG) and cytochrome P450 enzymes. Suppresses triacylglyceride (TAG) plasma excursion and adipose tissue TAG synthesis in rats. Reduces body weight of diet-induced obese rats. Cell permeable and orally bioavailable.

Specifications

Quantity 10 mg
Product Type AZD 3988
Purity >98%
Molecular Weight (g/mol) 456.44
Inhibitors AZD 3988

For Research Use Only

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