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Tocris Bioscience™ AZD 5438
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Catalog No. 396850
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Catalog No. Quantity
39-685-0 50 mg
39-681-0 10 mg
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Catalog No. 39-685-0 Supplier Tocris Bioscience™ Supplier No. 3968/50
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Description

Cdk inhibitor; potently inhibits cdk1, 2, 5 and 9

Potent inhibitor of cyclin dependent kinases (cdks; reported IC50 values are 6 - 45, 14, 16 and 20 nM for cdk2, cdk5, cdk1 and cdk9 respectively). Also inhibits cdk4 and cdk7 in the sub micromolar range. Exhibits antiproliferative activity in human tumor cell lines. Blocks cell cycling at G2-M, S and G1 phases; reduces the proportion of actively cycling cells in vivo.

Chemical Identifiers

CAS 602306-29-6
Molecular Formula C18H21N5O2S

Specifications

Quantity 50 mg
Formula Weight 371.46
Purity >99%
Molecular Weight (g/mol) 371.459
Chemical Name or Material AZD 5438

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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