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  5. Tocris Bioscience™ AZD 8055

Tocris Bioscience™ AZD 8055
GREENER_CHOICE

Catalog No. 784050
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Highly potent and selective mTOR inhibitor

AZD 8055 is a highly potent, selective and ATP-competitive mTOR inhibitor (IC50 = 0.8 nM). Inhibits growth and induces autophagy in a range of cancer cell lines and xenografts, including NSCLC and glioblastoma (IC50 values are 20, 50 and 53 nM in H838, A549 and U87MG cell lines, respectively). Orally bioavailable.

Specifications

Chemical Name or Material 5-[2,4-Bis[(3S)-3-methyl-4-morpholinyl]pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol
CAS 1009298-09-2
Quantity 50 mg
Target mTOR Inhibitors
Molecular Formula C25H31N5O4
Purity 0.98
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