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Invitrogen™ AZGP1 Recombinant Rabbit Monoclonal Antibody (7I8N3)
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Catalog No. PIMA535153
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PIMA535153 100 μL
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Catalog No. PIMA535153 Supplier Invitrogen™ Supplier No. MA535153
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: MVRMVPVLLS LLLLLGPAVP QENQDGRYSL TYIYTGLSKH VEDVPAFQAL GSLNDLQFFR YNSKDRKSQP MGLWRQVEGM EDWKQDSQLQ KAREDIFMET.

Alpha-2-glycoprotein 1, zinc-binding (AZGP1) is a gene encoding a protein that belongs to the immunoglobulin superfamily. This protein is abundant in various body fluids, such as blood plasma and milk, and is involved in lipid mobilization. AZGP1 is expressed in numerous tissues, including the liver, prostate, and adipose tissue, where it plays a significant role in the regulation of lipid metabolism and adipocyte function. It acts as an adipokine, influencing the breakdown and mobilization of fats, thereby contributing to energy homeostasis. In cancer research, AZGP1 has been highlighted for its potential as a prognostic biomarker, particularly in prostate and breast cancer, where lower expression levels are often associated with poor prognosis. Recent studies have also linked AZGP1 to cachexia, an extreme form of weight loss and muscle wasting, by promoting lipid mobilization in adipose tissue and influencing systemic catabolic states. Due to its multifaceted roles in lipid metabolism and disease processes, AZGP1 is considered a promising target for therapeutic interventions in metabolic and cancer-related disorders.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AZGP1
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 7I8N3
Concentration 0.38 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene AZGP1
Gene Accession No. P25311, Q63678
Gene Alias alpha-2 - glycoprotein 1 zinc; alpha-2 - glycoprotein 1, zinc; alpha-2-glycoprotein 1, zinc; alpha-2-glycoprotein 1, zinc-binding; Alpha-2-glycoprotein, zinc; Azgp1; major histocompatibility complex class I-like protein; testicular tissue protein Li 227; ZA2G; ZA2GA; Zag; Zinc a 2 glycoprotein; Zinc a2glycoprotein; Zinc alpha2glycoprotein; zinc alpha-2-glycoprotein 1; Zinc a 2 glycoprotein; Zinc a2glycoprotein; zinc-alpha-2-glycoprotein; Zn - alpha2 - glycoprotein; Zn a 2 glycoprotein; Zn a 2 GP; Zn alpha 2 glycoprotein; Zn alpha 2 GP; Zn a 2 glycoprotein; Zn a 2 GP; Zna2gp; zn-alpha-2-glycoprotein; Zn-alpha2-glycoprotein; zn-alpha-2-GP; ZNGP1
Gene Symbols AZGP1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Zinc-a2-glycoprotein (ZAG/AZGP1) (P25311).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25294, 563
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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