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Tocris Bioscience™ Azidothymidine

Catalog No. 415050
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Quantity:
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective reverse transcriptase inhibitor; antiretroviral

Selective reverse transcriptase inhibitor. Exhibits 100-fold selectivity for HIV reverse transcriptase over DNA polymerase α. Suppresses HIV-1 replication and enhances cell viability in HIV-1 infected T cells. Attenuates growth of multiple myeloma (MM) cells in vitro and reduces growth of MM tumor xenografts in mice. Increases differentiation iPSCs into cortical neurons and reduces the over-proliferation of neural precursors. Orally bioavailable and brain penetrant. Antiretroviral agent. Also decreases CRISPR-mediated homology directed repair (HDR) efficiency.

Specifications

Purity 99%
Molecular Formula 3 '-Azido-3 '-deoxythymidine
CAS 30516-87-1
Content And Storage -20°C
Quantity 50 mg
Product Type Azidothymidine
Molecular Weight (g/mol) M.W. (Observed): 267.24
Inhibitors Azidothymidine

For Research Use Only

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