Invitrogen™ AZIN1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5118954

Catalog No. PIPA5118954

Description

AZIN1 Polyclonal Antibody for Western Blot, IHC (P)

Antizyme inhibitor (AZIN1) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding. Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production.

Specifications

• Antigen: AZIN1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AZIN1
• Gene Alias: 1700085L02Rik; antizyme inhibitor 1; AZI; AZIA1; AZIN1; O OAZIN; OAZI; Oazin; ODC antizyme inhibitor; ODC1L; Ornithine decarboxylase antizyme inhibitor
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51582
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.61 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: O14977
• Gene Symbols: AZIN1
• Immunogen: Recombinant protein Antizyme Inhibitor 1. The antigen corresponds to amino acid range 5-290 of the target protein.
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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