Invitrogen™ AZIN1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5109436

Catalog No. PIPA5109436

Description

Immunogen sequence: AKKVVENDKF PSGVEKTGSD EPAFMYYMND GVYGSFASKL SEDLNTIPEV HKKYKEDEPL FTSSLWGPSC DELDQIVESC LLPELNVGDW LIFDNMGADS FHEPSAFNDF QRPAIYYMMS FSDWYEMQDA GITSDSMMKN FFFVPSCIQL SQEDSFSAEA.

Antizyme inhibitor (AZIN1) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding. Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production.

Specifications

• Antigen: AZIN1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AZIN1
• Gene Alias: 1700085L02Rik; antizyme inhibitor 1; AZI; AZIA1; AZIN1; O OAZIN; OAZI; Oazin; ODC antizyme inhibitor; ODC1L; Ornithine decarboxylase antizyme inhibitor
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51582, 54375, 58961
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.53 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O14977, O35484, Q63764
• Gene Symbols: AZIN1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 289-448 of human AZIN1 (NP_056962.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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