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Invitrogen™ AZIN1 Polyclonal Antibody
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Catalog No. PIPA5109436
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100 μL
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PIPA5109436 100 μL
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Catalog No. PIPA5109436 Supplier Invitrogen™ Supplier No. PA5109436
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: AKKVVENDKF PSGVEKTGSD EPAFMYYMND GVYGSFASKL SEDLNTIPEV HKKYKEDEPL FTSSLWGPSC DELDQIVESC LLPELNVGDW LIFDNMGADS FHEPSAFNDF QRPAIYYMMS FSDWYEMQDA GITSDSMMKN FFFVPSCIQL SQEDSFSAEA.

Antizyme inhibitor (AZIN1) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding. Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AZIN1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.53 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene AZIN1
Gene Accession No. O14977, O35484, Q63764
Gene Alias 1700085L02Rik; antizyme inhibitor 1; AZI; AZIA1; AZIN1; O OAZIN; OAZI; Oazin; ODC antizyme inhibitor; ODC1L; Ornithine decarboxylase antizyme inhibitor
Gene Symbols AZIN1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 289-448 of human AZIN1 (NP_056962.2).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51582, 54375, 58961
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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