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  6. Tocris Bioscience™ B I09
  7. 600950

Tocris Bioscience™ B I09

IRE1 endonuclease inhibitor; cell permeable

Supplier:  Tocris Bioscience™ 6009/50

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Catalog No. 60-095-0


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Description

Description

B I09 is an IRE-1 RNase inhibitor (IC50 = 1.23 μM). Inhibits IRE-1/XBP1 pathway. Cell permeable. Inhibits growth of human chronic lymphocytic leukemia (CLL) cells in vitro and promotes CLL regression in a mouse model.
Specifications

Specifications

Beige
1607803-67-7
303.31g/mol
Store at -20°C
50 mg
Inhibitor
C16H17NO5
Soluble to 50mM in DMSO
Inhibits Rnase
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