Invitrogen™ B-Myb Polyclonal Antibody

Catalog No.	Quantity
PIPA5143886	100 μg

Catalog No. PIPA5143886 Supplier Invitrogen™ Supplier No. PA5143886

Description

Rabbit Polyclonal Antibody

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human Raji whole cell, human HEK293 whole cell, human Caco-2 whole cell. ICC/IF: CACO-2 cell. Flow: U937 cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.

Specifications

• Antigen: B-Myb
• Applications: ELISA, Flow Cytometry, Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 500 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 4mg trehalose and no preservative
• Gene: Mybl2
• Gene Accession No.: P10244
• Gene Alias: B Myb; Bmyb; B-Myb; HGNC:7548; MGC15600; MYB proto-oncogene like 2; Mybl2; myb-like protein 2; Myb-related protein B; myeloblastosis oncogene-like 2; v-myb avian myeloblastosis viral oncogene homolog-like 2; v-myb myeloblastosis viral oncogene homolog (avian)-like 2; v-myb myeloblastosis viral oncogene homolog-like 2
• Gene Symbols: Mybl2
• Host Species: Rabbit
• Immunogen: E.coli-derived human B MyB/MYBL2 recombinant protein (Position: K31-R695).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4605
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG