Invitrogen™ B-Myb Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA579713

Catalog No. PIPA579713

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Raji whole cell. IHC: human tonsil tissue, mouse liver tissue, rat liver tissue.

Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.

Specifications

• Antigen: B-Myb
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Mybl2
• Gene Alias: B Myb; Bmyb; B-Myb; HGNC:7548; MGC15600; MYB proto-oncogene like 2; Mybl2; myb-like protein 2; Myb-related protein B; myeloblastosis oncogene-like 2; v-myb avian myeloblastosis viral oncogene homolog-like 2; v-myb myeloblastosis viral oncogene homolog (avian)-like 2; v-myb myeloblastosis viral oncogene homolog-like 2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17865, 296344, 4605
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 4 mg trehalose and no preservative
• Gene Accession No.: P10244, P48972
• Gene Symbols: Mybl2
• Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human B MyB (1-17aa MSRRTRCEDLDELHYQD).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG