Invitrogen™ B3GNT3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA555045

Catalog No. PIPA555045

Description

Immunogen sequence: LLQDVPPSKC AQPVFLLLVI KSSPSNYVRR ELLRRTWGRE RKVRGLQLRL LFLVGTASNP HEARKVNRLL ELEAQTHGDI LQWDFHDSFF NLTLKQVLFL QWQETRCANA SFVLNGDDDV FAHTDNMVFY LQDHDPGRHL FV Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 73%.

This gene encodes a member of the beta-1, 3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein and contains a signal anchor that is not cleaved. It prefers the substrates of lacto-N-tetraose and lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains and the biosynthesis of the backbone structure of dimeric sialyl Lewis a. It plays dominant roles in L-selectin ligand biosynthesis, lymphocyte homing and lymphocyte trafficking.

Specifications

• Antigen: B3GNT3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: B3gnt3
• Gene Alias: 2210008L19Rik; B3GALT8; B3GAL-T8; B3gnt3; B3GN-T3; B3GNT-3; Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase; Beta-1,3-galactosyltransferase 8; Beta-1,3-GalTase 8; beta-1,3-Gn-T3; beta-1,3-N-acetylglucosaminyltransferase 3; beta-1,3-N-acetylglucosaminyltransferase bGnT-3; beta3GalT8; beta3Gn-T3; beta-3-Gx-T8; BGnT-3; core 1 beta-1,3-N-acetylglucosaminyltransferase; core 1 extending beta-1,3-N-acetylglucosaminyltransferase; Core1-beta3GlcNAcT; HP10328; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3; putative type II membrane protein; TMEM3; Transmembrane protein 3; UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 8; UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 8; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3; UNQ637/PRO1266
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10331
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.12 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9Y2A9
• Gene Symbols: B3gnt3
• Immunogen: Recombinant protein corresponding to Human B3GNT3. Recombinant protein control fragment (Product #RP-88799).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG