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Invitrogen™ B4GALT2 Polyclonal Antibody
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Catalog No. PIPA561580
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100 μL
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PIPA561580 100 μL
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Catalog No. PIPA561580 Supplier Invitrogen™ Supplier No. PA561580
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LPPCPDSPPG LVGRLLIEFT SPMPLERVQR ENPGVLMGGR YTPPDCTPAQ TVAVIIPFRH REH Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 90%.

B4GALT2 is one of type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity is affected by alpha-lactalbumin but it is not expressed in lactating mammary tissue.
TRUSTED_SUSTAINABILITY

Specifications

Antigen B4GALT2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene B4galt2
Gene Accession No. O60909
Gene Alias 4-Gal; B4galt2; B4Gal-T2; B4Gal-T3; Beta-1,4-galactosyltransferase 2; beta-1,4-galactosyltransferase II; beta-1,4-GalTase 2; beta-4-GalT2; beta4Gal-T2; Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase; beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase 2; Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase; Ggtb2; Lactose synthase A protein; N-acetyllactosamine synthase; Nal synthase; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 2; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2; UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 2; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 2; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 2
Gene Symbols B4galt2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human B4GALT2. Recombinant protein control fragment (Product #RP-100925).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8704
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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