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Invitrogen™ B4GALT4 Polyclonal Antibody
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Catalog No. PIPA589987
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PIPA589987 100 μL
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Catalog No. PIPA589987 Supplier Invitrogen™ Supplier No. PA589987
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VGAIQEIPKA KEFMANFHKT LILGKGKTLT NEASTKKVEL DNCPSVSPYL RGQSKLIFKP DLTLEEVQAE NPKVSRGRYR PQECKALQRV AILVPHRNRE KHLMYLLEHL HPFLQRQQLD YGIYVIHQAE GKKFNRAKLL NVGYLEALKE ENWDCFIFHD VDLVPENDFN LYKCEEHPKH LVVGRNSTGY RLRYSGYFGG VTALSREQFF KVNGFSNNYW GWGGEDDDLR LRVELQRMKI SRPLPEVGKY TMVFHTRDKG NEVNAERMKL LHQVSRVWRT DGLSSCSYKL VSVEHNPLYI NITVDFWFGA; Positive Samples: 293T, HT-29, Mouse kidney, Mouse thymus, Mouse lung, Rat kidney, Rat thymus, Rat lung; Cellular Location: Golgi apparatus, Golgi stack membrane, Single-pass type II membrane protein.

This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene appears to mainly play a role in glycolipid biosynthesis. Two alternatively spliced transcript variants have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen B4GALT4
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.48 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene B4GALT4
Gene Accession No. O60513, Q66HH1, Q9JJ04
Gene Alias 9130402O08Rik; B4GALT4; b4Gal-T4; B4galt-IV; Beta-1,4-galactosyltransferase 4; beta-1,4-galactosyltransferase IV; beta-1,4-GalTase 4; beta4Gal-T4; beta4GalT-IV; beta-N-acetylglucosaminyl; Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase; beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase 4; Lactotriaosylceramide beta-1,4-galactosyltransferase; N-acetyllactosamine synthase; Nal synthase; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 4; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4; UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 4; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 4; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 4; UNQ552/PRO1109
Gene Symbols B4GALT4
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 35-344 of human B4GALT4 (NP_0037691).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 303923, 56375, 8702
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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