Invitrogen™ B4GALT4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589987

Catalog No. PIPA589987

Description

Immunogen sequence: VGAIQEIPKA KEFMANFHKT LILGKGKTLT NEASTKKVEL DNCPSVSPYL RGQSKLIFKP DLTLEEVQAE NPKVSRGRYR PQECKALQRV AILVPHRNRE KHLMYLLEHL HPFLQRQQLD YGIYVIHQAE GKKFNRAKLL NVGYLEALKE ENWDCFIFHD VDLVPENDFN LYKCEEHPKH LVVGRNSTGY RLRYSGYFGG VTALSREQFF KVNGFSNNYW GWGGEDDDLR LRVELQRMKI SRPLPEVGKY TMVFHTRDKG NEVNAERMKL LHQVSRVWRT DGLSSCSYKL VSVEHNPLYI NITVDFWFGA; Positive Samples: 293T, HT-29, Mouse kidney, Mouse thymus, Mouse lung, Rat kidney, Rat thymus, Rat lung; Cellular Location: Golgi apparatus, Golgi stack membrane, Single-pass type II membrane protein.

This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene appears to mainly play a role in glycolipid biosynthesis. Two alternatively spliced transcript variants have been found for this gene.

Specifications

• Antigen: B4GALT4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: B4GALT4
• Gene Alias: 9130402O08Rik; B4GALT4; b4Gal-T4; B4galt-IV; Beta-1,4-galactosyltransferase 4; beta-1,4-galactosyltransferase IV; beta-1,4-GalTase 4; beta4Gal-T4; beta4GalT-IV; beta-N-acetylglucosaminyl; Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase; beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase 4; Lactotriaosylceramide beta-1,4-galactosyltransferase; N-acetyllactosamine synthase; Nal synthase; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 4; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4; UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 4; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 4; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 4; UNQ552/PRO1109
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 303923, 56375, 8702
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.48 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O60513, Q66HH1, Q9JJ04
• Gene Symbols: B4GALT4
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 35-344 of human B4GALT4 (NP_0037691).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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