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B7-H3 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501729463 Shop All Proteintech Group Inc Products
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50-172-9463 150 μL
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Catalog No. 50-172-9463 Supplier Proteintech Group Inc Supplier No. 144531AP150UL
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Description

Rabbit Polyclonal Antibody

CD276 is a member of the B7 family of co-stimulatory molecules also known as B7-H3. CD276 is a type I transmembrane protein that induces the proliferation of CD4+ and CD8+ T cells, enhances the generation of cytotoxic T cells and selectively stimulates the production of interferon gamma. Expression of CD276 can be induced on dendritic cells and monocytes by inflammatory cytokines, and is also widely expressed in peripheral tissues including the heart, kidney, testis and colon. In humans, CD276 exists as two isoforms which result from gene duplication and differential splicing. CD276 is reported to have therapeutic potential for the regulation of cell-mediated immune responses to cancer, particularly in conjunction with anti-angiogenic therapy.

Specifications

Antigen B7-H3
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.19 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CD276
Gene Accession No. Q5ZPR3
Gene Alias 4Ig B7 H3, B7 homolog 3, B7-H3, CD276, CD276 antigen, CD276 molecule, Costimulatory molecule, UNQ309/PRO352
Gene Symbols CD276
Host Species Rabbit
Immunogen B7-H3 Fusion Protein Ag6006
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 80381
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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