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Invitrogen™ B7-H3 Recombinant Rabbit Monoclonal Antibody (317), Invitrogen™
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Catalog No. PIMA543070
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PIMA543070 100 μL
PIMA543464 50 μL
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Catalog No. PIMA543070 Supplier Invitrogen™ Supplier No. MA543070
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Rabbit Recombinant Monoclonal Antibody

Specificity: Mouse B7-H3/CD276

CD276 is a member of the B7 family of co-stimulatory molecules also known as B7-H3. CD276 is a type I transmembrane protein that induces the proliferation of CD4+ and CD8+ T cells, enhances the generation of cytotoxic T cells and selectively stimulates the production of interferon gamma. Expression of CD276 can be induced on dendritic cells and monocytes by inflammatory cytokines, and is also widely expressed in peripheral tissues including the heart, kidney, testis and colon. In humans, CD276 exists as two isoforms which result from gene duplication and differential splicing. CD276 is reported to have therapeutic potential for the regulation of cell-mediated immune responses to cancer, particularly in conjunction with anti-angiogenic therapy.
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Specifications

Antigen B7-H3
Applications ELISA
Classification Recombinant Monoclonal
Clone 317
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene CD276
Gene Accession No. Q8VE98
Gene Alias 4Ig-B7-H3; 6030411F23Rik; AU016588; B7 homolog 3; B7h3; B7-H3; B7RP-2; CD276; CD276 antigen; CD276 molecule; CD276 molecule tv1; costimulatory molecule; PSEC0249; sB7 H3; sB7H3; sCD276; soluble B7 H3; soluble B7H3; soluble CD276; UNQ309/PRO352
Gene Symbols CD276
Host Species Rabbit
Immunogen Recombinant Mouse B7-H3/CD276 Protein.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 102657
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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