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Invitrogen™ B7-H6 Polyclonal Antibody
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Catalog No. PA549085
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400 μL
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PA549085 400 μL
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Catalog No. PA549085 Supplier Invitrogen™ Supplier No. PA549085
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Description

Rabbit Polyclonal Antibody

B7-H6 Polyclonal Antibody for Western Blot

B7-H6 (NCR3LG1) is a transmembrane endogenous ligand expressed on the surfaces of tumor cells. B7-H6 binds with NKp30 present on NK cells. Binding of B7-H6 to NKp30 causes the ligation of NKp30 subsequently inducing NK cell activation and target cell cytolysis. B7-H6 is not constitutively expressed on normal tissue. Whether it can be expressed endogenously under certain conditions is under investigation. B7-H6 has been detected on circulating pro-inflammatory CD14(+)CD16(+) monocytes in some patients with sepsis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen B7-H6
Applications Western Blot
Classification Polyclonal
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene NCR3LG1
Gene Accession No. Q68D85
Gene Alias B7 homolog 6; B7H6; B7-H6; DKFZp686I21167; DKFZp686O24166; natural cytotoxicity triggering receptor 3 ligand 1; natural killer cell cytotoxicity receptor 3 ligand 1; NCR3LG1; putative Ig-like domain-containing protein DKFZp686O24166/DKFZp686I21167
Gene Symbols NCR3LG1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 389-415 amino acids from the C-terminal region of human B7H6.
Purification Method Antigen affinity chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 374383
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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