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B7-H6 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501982341
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50-198-2341 100 μL
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Catalog No. 50-198-2341 Supplier Bioss Supplier No. BS12559R
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Description

Rabbit Polyclonal Antibody

B7-H6 (NCR3LG1) is a transmembrane endogenous ligand expressed on the surfaces of tumor cells. B7-H6 binds with NKp30 present on NK cells. Binding of B7-H6 to NKp30 causes the ligation of NKp30 subsequently inducing NK cell activation and target cell cytolysis. B7-H6 is not constitutively expressed on normal tissue. Whether it can be expressed endogenously under certain conditions is under investigation. B7-H6 has been detected on circulating pro-inflammatory CD14(+)CD16(+) monocytes in some patients with sepsis.

Specifications

Antigen B7-H6
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene NCR3LG1
Gene Accession No. Q68D85
Gene Alias B7 homolog 6; B7H6; B7-H6; DKFZp686I21167; DKFZp686O24166; Natural cytotoxicity triggering receptor 3 ligand 1; natural killer cell cytotoxicity receptor 3 ligand 1; NCR3LG1; putative Ig-like domain-containing protein DKFZp686O24166/DKFZp686I21167
Gene Symbols NCR3LG1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human B7-H6.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 374383
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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