Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA565868

Invitrogen™ BABAM1 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA565868
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA565868 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA565868 Supplier Invitrogen™ Supplier No. PA565868
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Immunogen sequence: EEEHSAEPRPR TRSNPEGAED RAVGAQASVG SRSEGEGEAA SADDGSLNTS GAGPKSWQVP PPAPEVQIRT PRVNCPEKVI ICL Highest antigen sequence identity to the following orthologs - mouse 80%, rat 80%.

HSPC142 is a component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it is required for the complex integrity and its localization at DSBs. HSPC142 probably also plays a role as a component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin. In these 2 complexes, it is probably required to maintain the stability of BRE/BRCC45 and help the 'Lys-63'-linked deubiquitinase activity mediated by BRCC3/BRCC36.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BABAM1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene BABAM1
Gene Accession No. Q9NWV8
Gene Alias 5430437P03Rik; BABAM1; BRCA1-A complex subunit MERIT40; BRISC and BRCA1 A complex member 1; BRISC and BRCA1-A complex member 1; C19orf62; HSPC142; mediator of Rap80 interactions and targeting 40 kDa; mediator of RAP80 interactions and targeting subunit of 40 kDa; MERIT40; NBA1; new component of the BRCA1 A complex; new component of the BRCA1-A complex; new component of the BRCAA1 A complex
Gene Symbols BABAM1
Host Species Rabbit
Immunogen Recombinant Human BABAM1. Recombinant protein control fragment (Product #RP-104996).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29086
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.