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BACE1 Mouse anti-Human, Mouse, Rat, Clone: 3C1C3, Abnova™

Catalog No. 89933619 Shop All Abnova Corporation Products
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89-933-619 100 μg
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Catalog No. 89-933-619 Supplier Abnova Corporation Supplier No. MAB12256
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Description

Mouse monoclonal antibody raised against partial recombinant human BACE1.

Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]

Specifications

Antigen BACE1
Applications ELISA, Flow Cytometry, Immunofluorescence, Western Blot
Classification Monoclonal
Clone 3C1C3
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against partial recombinant human BACE1.
Dilution ELISA (1:10000) Flow Cytometry (1:200-1:400) Immunofluorescence (1:200-1:1000) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.05% sodium azide)
Gene Alias ASP2/BACE/FLJ90568/HSPC104/KIAA1149
Gene Symbols BACE1
Host Species Mouse
Immunogen Recombinant protein corresponding to amino acids 112-324 of human BACE1.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23621
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1
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