BACE2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 163211AP150UL

Catalog No. 50-173-0871

Description

Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer′s disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by this gene. This gene localizes to the ′Down critical region′ of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene.

Specifications

• Antigen: BACE2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BACE2
• Gene Alias: AEPLC, ALP56, Asp 1, ASP1, ASP21, Aspartic like protease 56 kDa, Aspartyl protease 1, BACE2, BAE2, Beta secretase 2, CDA13, CEAP1, Down region aspartic protease, DRAP, Memapsin 1, Theta secretase, UNQ418/PRO852
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 25825, 288227, 56175
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.13 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q6IE75, Q9JL18, Q9Y5Z0
• Gene Symbols: Bace2
• Immunogen: BACE2 Fusion Protein Ag9404
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG