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Invitrogen™ BAD Polyclonal Antibody
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Catalog No. PIPA585624
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100 μL
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PIPA585624 100 μL
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Catalog No. PIPA585624 Supplier Invitrogen™ Supplier No. PA585624
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Description

Rabbit Polyclonal Antibody

Keep as concentrated solution. Predicted reactivity: Rhesus Monkey (95%), Chimpanzee (100%). Positive Control: 293T, A431, HeLa. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by BAD is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BAD
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1.36 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene BAD
Gene Accession No. Q92934
Gene Alias AI325008; BAD; Bbc2; Bbc6; Bcl2 antagonist of cell death; BCL2 associated agonist of cell death; bcl-2 associated death agonist; Bcl2-antagonist of cell death; BCL2-antagonist of cell death protein; bcl2-associated agonist of cell death; bcl2-associated death promoter; bcl-2-binding component 6; BCL2-binding component 6; BCL2-binding protein; BCL2L8; bcl2-L-8; Bcl-2-like protein 8; BCL-X/BCL-2 binding protein; bcl-XL/Bcl-2-associated death promoter; hypothetical protein LOC615013; OTTMUSP00000017561; OTTMUSP00000022400
Gene Symbols BAD
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human Bad. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 572
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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