Invitrogen™ BAD Recombinant Rabbit Monoclonal Antibody (SA32-01)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA531978

Catalog No. PIMA531978

Description

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

The protein encoded by BAD is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.

Specifications

• Antigen: BAD
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: O35147, Q61337, Q92934
• Gene Symbols: BAD
• Immunogen: Synthetic peptide within Human Bad aa 1-50.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
• Clone: SA32-01
• Conjugate: Unconjugated
• Gene: BAD
• Gene Alias: AI325008; BAD; Bbc2; Bbc6; Bcl2 antagonist of cell death; BCL2 associated agonist of cell death; bcl-2 associated death agonist; Bcl2-antagonist of cell death; BCL2-antagonist of cell death protein; bcl2-associated agonist of cell death; bcl2-associated death promoter; bcl-2-binding component 6; BCL2-binding component 6; BCL2-binding protein; BCL2L8; bcl2-L-8; Bcl-2-like protein 8; BCL-X/BCL-2 binding protein; bcl-XL/Bcl-2-associated death promoter; hypothetical protein LOC615013; OTTMUSP00000017561; OTTMUSP00000022400
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 12015, 572, 64639
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid