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BAF53A Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501982349
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50-198-2349 100 μL
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Catalog No. 50-198-2349 Supplier Bioss Supplier No. BS12568R
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Description

Rabbit Polyclonal Antibody

BAF53A is a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.

Specifications

Antigen BAF53A
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Actl6a
Gene Accession No. O96019
Gene Alias 2810432C06Rik; 53 kDa BRG1-associated factor A; actin like 6A; actin-like 6; actin-like 6A; actin-like 6B; Actin-like protein 6A; actin-related protein 4; Actin-related protein Baf53a; Actl6; ACTL6A; ACTL6B; AI851094; ARP4; ArpNbeta; ARPN-BETA; BAF complex 53 kDa subunit; BAF53; BAF53A; BAF53B; BRG1/brm-associated factor 53A; BRG1-associated factor 53A; C79802; hArpN alpha; hArpN beta; INO80 complex subunit K; INO80K; MGC5382; MGC5382 Arp4; RGD1307747
Gene Symbols Actl6a
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human BAF53A.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 86
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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