Invitrogen™ BAF53A Recombinant Rabbit Monoclonal Antibody (5H3L6)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ 702414

Catalog No. PI702414

Description

This antibody is predicted to react with Monkey, Pig, Rat Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

BAF53A is a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.

Specifications

• Antigen: BAF53A
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: O96019, Q9Z2N8
• Gene Symbols: Actl6a
• Immunogen: Peptide corresponding to human BAF53A (aa124-142).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot, Immunocytochemistry
• Clone: 5H3L6
• Conjugate: Unconjugated
• Gene: Actl6a
• Gene Alias: 2810432C06Rik; 53 kDa BRG1-associated factor A; actin like 6A; actin-like 6; actin-like 6A; actin-like 6B; actin-like protein 6A; actin-related protein 4; actin-related protein Baf53a; Actl6; Actl6a; ACTL6B; AI851094; ARP4; ArpNbeta; ARPN-BETA; BAF complex 53 kDa subunit; BAF53; Baf53a; BAF53B; BRG1/brm-associated factor 53A; BRG1-associated factor 53A; C79802; hArpN alpha; hArpN beta; INO80 complex subunit K; INO80K; MGC5382; MGC5382 Arp4; RGD1307747
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 361925, 56456, 86
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov