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BAF57/SMARCE1 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501558505
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50-155-8505 20 μL
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Catalog No. 50-155-8505 Supplier Bethyl Laboratories, Inc Supplier No. A300810AT
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.

Specifications

Antigen BAF57/SMARCE1
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene SMARCE1
Gene Accession No. O54941, Q969G3
Gene Alias SMARCE1; BAF57; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1; mammalian chromatin remodeling complex BRG1-associated factor 57; BAF57; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin e1
Gene Symbols SMARCE1
Host Species Rabbit
Immunogen Between 360 and C-term
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57376, 6605
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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