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Invitrogen™ BAFF Monoclonal Antibody (2B)
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Catalog No. PIMA182774
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500 μg
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PIMA182774 500 μg
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Catalog No. PIMA182774 Supplier Invitrogen™ Supplier No. MA182774
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Description

Mouse Monoclonal Antibody

Reconstitute with 0.5 mL of distilled water. Prior to reconstitution, store at 4°C. After reconstitution, store undiluted at -20°C, avoiding freeze/thaw cycles. Mouse anti Human CD257 antibody, clone 2B recognizes CD257, also known as BAFF/BLyS.

BAFF is a membrane bound cytokine expressed by B cell lineage cells. The soluble form of the cytokine binds to the receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. BAFF is a potent B cell activator, and important for the proliferation and differentiation of B cells. BAFF is also expressed by T lymphocytes and has been shown to promote T cell activation and survival. Isoforms representing alternatively spliced, and glycosylated variants have been identified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BAFF
Applications ELISA
Classification Monoclonal
Clone 2B
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.2
Gene TNFSF13B
Gene Accession No. Q9Y275
Gene Alias ApoL related ligand TALL-1; b cell-activating factor; B lymphocyte stimulator; BAFF; B-cell-activating factor; B-lymphocyte stimulator; BLYS; CD257; D8Ertd387e; delta BAFF; Delta4 BAFF; dendritic cell-derived TNF-like molecule; DTL; RGD1561519; TALL1; TALL-1; THANK; TNF- and APOL-related leukocyte expressed ligand 1; TNF and ApoL-related leukocyte expressed ligand 1; TNF homolog that activates apoptosis; Tnfsf13b; TNFSF20; TNLG7A; tumor necrosis factor (ligand) superfamily member 13b; tumor necrosis factor (ligand) superfamily, member 13b; tumor necrosis factor (ligand) superfamily, member 20; tumor necrosis factor ligand 7A; tumor necrosis factor ligand superfamily member 13B; Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form; tumor necrosis factor superfamily member 13b; tumor necrosis factor-like protein ZTNF4; UNQ401/PRO738; ZTNF4
Gene Symbols TNFSF13B
Host Species Mouse
Immunogen Recombinant full length mature human CD257.
Purification Method Protein G
Quantity 500 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10673
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG1
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Safety and Handling

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