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  5. Tocris Bioscience™ BAG 956

Tocris Bioscience™ BAG 956

Catalog No. 360650R
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Dual PI 3-kinase and PDPK1 (PDK1) inhibitor

BAG 956 is a dual PDPK1 (PDK1) and class I PI 3-K inhibitor (IC50 values are 245, 56, 446, 35 and 117 nM for PDPK1 and PI 3-K p110 -α, -β, -δ, and -γ respectively). Inhibits cellular AKT phosphorylation at Thr308. Blocks cell proliferation, causing arrest in G1 phase of the cell cycle. Slows tumor progression in mouse xenograft models.

Specifications

Purity 98%
Content And Storage Store at -20°C
Quantity 50 mg
Product Type BAG 956
Molecular Weight (g/mol) 427.5
Inhibitors BAG 956

For Research Use Only

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