Invitrogen™ BAG1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588066

Catalog No. PIPA588066

Description

Immunogen sequence: MNRSQEVTRD EESTRSEEVT REEMAAAGLT VTVTHSNEKH DLHVTSQQGS SEPVVQDLAQ VVEEVIGVPQ SFQKLIFKGK SLKEMETPLS ALGIQDGCRV MLIGKKNSPQ EEVELKKLKH LEKSVEKIAD QLEELNKELT GIQQGFLPKD LQAEALCKLD RRVKATIEQF MKILEEIDTL ILPENFKDSR LKRKGLVKKV QAFLAECDTV EQNICQETER LQSTNFALAE; Positive Samples: SW620, Mouse kidney; Cellular Location: Cytoplasm, Cytoplasm, Nucleus.

The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. At least three protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) start site, and alternative, downstream, AUG translation initiation sites.

Specifications

• Antigen: BAG1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Bag1
• Gene Alias: BAG family molecular chaperone regulator 1; Bag1; BAG-1; BCL2 associated athanogene 1; Bcl-2 associating athanogene-1 protein; BCL2-associated athanogene; bcl-2-associated athanogene 1; BCL2-associated athanogene 1; Bcl-2-binding protein; glucocortoid receptor-associated protein RAP46; HAP; Rap46; receptor-associated protein, 46-KD; RP11-326F20.2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12017, 573
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 0.33 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q60739, Q99933
• Gene Symbols: Bag1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human BAG1 (NP_0011658861).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG