Invitrogen™ BAG1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578851

Catalog No. PIPA578851

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Hela whole cell, human Jurkat whole cell, human MCF-7 whole cell, human 293T whole cell. IHC: human breast cancer tissue, human colorectal adenocarcinoma tissue, human tonsil tissue, mouse colon tissue, rat colon tissue.

The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. At least three protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) start site, and alternative, downstream, AUG translation initiation sites.

Specifications

• Antigen: BAG1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Bag1
• Gene Alias: BAG family molecular chaperone regulator 1; Bag1; BAG-1; BCL2 associated athanogene 1; Bcl-2 associating athanogene-1 protein; BCL2-associated athanogene; bcl-2-associated athanogene 1; BCL2-associated athanogene 1; Bcl-2-binding protein; glucocortoid receptor-associated protein RAP46; HAP; Rap46; receptor-associated protein, 46-KD; RP11-326F20.2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12017, 297994, 573
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and no preservative
• Gene Accession No.: B0K019, Q60739, Q99933
• Gene Symbols: Bag1
• Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Bag1 (323-345aa DTVEQNICQETERLQSTNFALAE).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov