Invitrogen™ BAG2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA582707

Catalog No. PIPA582707

Description

Immunogen sequence: SACSSEVPHG PVDQKFQSIV IGCALEDQKK IKRRLETLLR NIENSDKAIK LLEHSKGAGS KTLQQNAES.

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

Specifications

• Antigen: BAG2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BAG2
• Gene Alias: 2610042A13Rik; BAG cochaperone 2; BAG family molecular chaperone regulator 2; BAG2; BAG-2; BAG-family molecular chaperone regulator-2; BC016230; BCL2 associated athanogene 2; Bcl-2-associated athanogene 2; Bcl2-associated athanogene 2; dJ417I1.2; dJ417I1.2 (BAG-family molecular chaperone regulator 2); KIAA0576; MGC149462; RP3-496N17.2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9532
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O95816
• Gene Symbols: BAG2
• Immunogen: Recombinant protein corresponding to Human BAG2. Recombinant protein control fragment (Product #RP-92023).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov