Invitrogen™ BAG2 Recombinant Rabbit Monoclonal Antibody (6D6Z0)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA542894

Catalog No. PIMA542894

Description

Positive test controls include: A-549, PC-3, Jurkat. Immunogen sequence: MAQAKINAKA NEGRFCRSSS MADRSSRLLE SLDQLELRVE ALREAATAVE QEKEILLEMI HSIQNSQDMR QISDGEREEL NLTANRLMGR TLTVEVSVET.

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

Specifications

• Antigen: BAG2
• Classification: Recombinant Monoclonal
• Concentration: 0.34 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O95816, Q91YN9
• Gene Symbols: BAG2
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BAG2 (O95816).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Clone: 6D6Z0
• Conjugate: Unconjugated
• Gene: BAG2
• Gene Alias: 2610042A13Rik; BAG cochaperone 2; BAG family molecular chaperone regulator 2; BAG2; BAG-2; BAG-family molecular chaperone regulator-2; BC016230; BCL2 associated athanogene 2; Bcl-2-associated athanogene 2; Bcl2-associated athanogene 2; dJ417I1.2; dJ417I1.2 (BAG-family molecular chaperone regulator 2); KIAA0576; MGC149462; RP3-496N17.2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 213539, 690038, 9532
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov