Invitrogen™ BAG3 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA5142301

Catalog No. PIPA5142301

Description

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.

BAG3 are among BAG proteins that compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

Specifications

• Antigen: BAG3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BAG3
• Gene Alias: AA407278; BAG family molecular chaperone regulator 3; BAG3; BAG-3; BCL2 associated athanogene 3; Bcl-2-associated athanogene 3; Bcl2-associated athanogene 3; BCL2-binding athanogene 3; bcl-2-binding protein Bis; Bcl-2-interacting death suppressor; BIS; CAIR-1; DKFZp434E0610; docking protein CAIR-1; MFM6; mg638; MGC104307; MNCb-2243
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 9531
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O95817
• Gene Symbols: BAG3
• Immunogen: Peptide with sequence C-KNAGNAEDPHTE (aa 537-548).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG