BAG3 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-6813	100 μL

Catalog No. 50-198-6813 Supplier Bioss Supplier No. BS5799R

Description

Rabbit Polyclonal Antibody

BAG3 are among BAG proteins that compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

Specifications

• Antigen: BAG3
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: BAG3
• Gene Accession No.: O95817
• Gene Alias: AA407278; BAG family molecular chaperone regulator 3; BAG3; BAG-3; BCL2 associated athanogene 3; Bcl-2-associated athanogene 3; BCL2-associated athanogene 3; BCL2-binding athanogene 3; Bcl-2-binding protein Bis; Bcl-2-interacting death suppressor; Bis; CAIR-1; DKFZp434E0610; Docking protein CAIR-1; MFM6; mg638; MGC104307; MNCb-2243
• Gene Symbols: BAG3
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human BAG3.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 9531
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG