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Invitrogen™ BAG5 Polyclonal Antibody
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Catalog No. PIPA596429
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100 μL
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PIPA596429 100 μL
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Catalog No. PIPA596429 Supplier Invitrogen™ Supplier No. PA596429
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GVLIALLMGV NNNETCRHLS CVLSGLIADL DALDVCGRTE IRNYRREVVE DINKLLKYLD LEEEADTTKA FDLRQNHSIL KIEKVLKRMR EIKNELLQAQ NPSELYLSSK TELQGLIGQL DEVSLEKNPC IREARRRAVI EVQTLITYID LKEALEKRKL FACEEHPSHK AVWNVLGNLS EIQGEVLSFD GNRTDKNYIR LEELLTKQLL ALDAVDPQGE EKCKAARKQA VRLAQNILSY LDLKSDEWEY; Positive Samples: SH-SY5Y, MCF7, Mouse lung, Mouse testis, Rat brain, Rat lung.

It has been hypothesizes that the BAG-5 protein will induce the death of nigral neurons through its predicted interaction with hsp70, which will cause increased protein aggregation and cell death by disinhibition of hsp70's anti-apoptotic function. It is believed that BAG-5 will play an important role in the mechanisms of neuronal death. BAG-5 may also be of interest due to its possible role as a modulator of the hsp70/hsp40 chaperone axis or its possible interaction and coordination of localization/ modulation of other BAG containing proteins via BAG-BAG heterodimerization.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BAG5
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.58 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene BAG5
Gene Accession No. Q5QJC9, Q8CI32, Q9UL15
Gene Alias 1600025G07Rik; 4930405J06Rik; BAG cochaperone 5; BAG family molecular chaperone regulator 5; Bag5; BAG-5; BAG-family molecular chaperone regulator-5; BAG-family molecular chaperone regulator-5 (BAG-5); BCL2 associated athanogene 5; Bcl-2-associated athanogene 5; BCL2-associated athanogene 5; KIAA0873; LOC522854 protein
Gene Symbols BAG5
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 198-447 of human BAG5 (NP_0048641).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 366734, 70369, 9529
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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