Invitrogen™ BAG5 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518817

Catalog No. PIPA518817

Description

This antibody is predicted to react with mouse and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.

It has been hypothesizes that the BAG-5 protein will induce the death of nigral neurons through its predicted interaction with hsp70, which will cause increased protein aggregation and cell death by disinhibition of hsp70's anti-apoptotic function. It is believed that BAG-5 will play an important role in the mechanisms of neuronal death. BAG-5 may also be of interest due to its possible role as a modulator of the hsp70/hsp40 chaperone axis or its possible interaction and coordination of localization/ modulation of other BAG containing proteins via BAG-BAG heterodimerization.

Specifications

• Antigen: BAG5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BAG5
• Gene Alias: 1600025G07Rik; 4930405J06Rik; BAG cochaperone 5; BAG family molecular chaperone regulator 5; Bag5; BAG-5; BAG-family molecular chaperone regulator-5; BAG-family molecular chaperone regulator-5 (BAG-5); BCL2 associated athanogene 5; Bcl-2-associated athanogene 5; BCL2-associated athanogene 5; KIAA0873; LOC522854 protein
• Host Species: Goat
• Purification Method: Ammonium Sulfate Precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 9529
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9UL15
• Gene Symbols: BAG5
• Immunogen: Synthetic peptide sequence (DPQGEEKCKAARKQ) corresponding to the internal amino acids of BAG5 (aa 413-427).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG