Invitrogen™ BAIAP2 Monoclonal Antibody (OTI 1D9)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA525560

Catalog No. PIMA525560

Description

BAIAP2 Monoclonal Antibody for Western Blot, ICC/IF, IHC (P), Flow

The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Specifications

• Antigen: BAIAP2
• Classification: Monoclonal
• Concentration: 0.65 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9UQB8
• Gene Symbols: BAIAP2
• Immunogen: Full length human recombinant protein of BAIAP2 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: OTI 1D9
• Conjugate: Unconjugated
• Gene: BAIAP2
• Gene Alias: BAI1 associated protein 2; BAI1-associated protein 2; BAIAP2; BAI-associated protein 2; BAP2; brain-specific angiogenesis inhibitor 1-associated protein 2; Fas ligand-associated factor 3; FLAF3; insulin receptor substrate 53; insulin receptor substrate of 53 kDa; insulin receptor substrate p53; insulin receptor substrate p53/p58; Insulin receptor substrate protein of 53 kDa; insulin receptor tyrosine kinase 53 kDa substrate; Insulin receptor tyrosine kinase substrate protein p53; IRS-58; IRSp53; IRSp53/58; R75030
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10458
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid